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Immunoglobulin G antibodies, immunoglobulin M antibodies, Sabin-Feldman dye test, IFA test, EIA test
This test looks for antibodies against Toxoplasma gondii (T. gondii) infection in your blood.
T. gondii is a parasite that can infect people when they:
Eat infected meat, especially lamb, venison, or pork, that hasn't been fully cooked
Eat food contaminated by knives, utensils, cutting boards, or other foods that have come in contact with the infected meat
Drink contaminated water
Swallow the parasite after being exposed to it while cleaning an infected cat's litter box
In healthy adults, this infection often doesn’t cause any symptoms. But in people whose immune system isn't working well, a T. gondii infection can cause brain damage and other serious problems. If a pregnant person is infected, it can cause stillbirth, severe birth defects, or problems that can be seen in the child years later.
You may need this test if your healthcare provider thinks that you have toxoplasmosis. Most people who are infected with T. gondii don’t know it. Symptoms can include:
Flu-like symptoms, such as achiness and swollen lymph nodes
Blurry vision, eye redness, and pain if the disease is affecting the eyes
A small number of infected infants have brain or eye damage at birth.
If you're pregnant, you may also have this test, especially if you may have been exposed to T. gondii.
Test results may vary depending on your age, gender, health history, and other things. Your test results may be different depending on the lab used. They may not mean you have a problem. Ask your healthcare provider what your test results mean for you.
Test results can show if you have higher levels of immunoglobulin G (IgG) or immunoglobulin M (IgM) antibodies that are related to T. gondii infection. IgM antibodies tend to show up faster and go away faster after an infection. IgG antibodies tend to slowly go away over the next 1 to 2 years.
The results can tell your healthcare provider if you have a new infection or had an infection in the past.
The test is done with a blood sample. A needle is used to draw blood from a vein in your arm or hand.
Having a blood test with a needle carries some risks. These include bleeding, infection, bruising, and feeling lightheaded. When the needle pricks your arm or hand, you may feel a slight sting or pain. Afterward, the site may be sore.
If you have AIDS and toxoplasmosis, you may have only a small rise in IgG. In this case, the results for IgM and other antibodies may show up as negative. Other factors aren't likely to affect your results.
Tell your healthcare provider if you have a condition that affects your immune system or are taking any medicines that may do so. It's best to be sure your provider knows about all the medicines, herbs, vitamins, and supplements you are taking. This includes medicines that don't need a prescription and any illegal drugs you may use.